The Church of St. Anthony of Padua in Ruscio, rebuilt after the 1703 earthquake, is situated on a land belonging to the Convent of St. Francis. It has a stucco altar with an inscription that mentions the "Sequeri", a popular prayer useful to find lost items if recited for thirteen times consecutive.

The Church of St. Anthony of Padua is a small building located in Ruscio "di sopra"( territory of Monteleone di Spoleto), next to the homonymous street of St. Anthony. The oldest church structure was destroyed during the earthquake of January 14^th, 1703. Also known as "Sant’ Antonio al piano di sotto", it is inserted in fact in the report list of dilapidated buildings needful of restoration work after the earthquake, which is sent a few months later by the Congregation of Monteleone inhabitants established by the Papal States (who ask for the tax exemption, money to rebuild the buildings and castle walls partially ruined, as well as to increase the number of soldiers on site). During the pastoral visit of the Lascaris on 1712 (in the report a primitive church dedicated to San Lorenzo with a hospital is asked), the new chapel is already rebuilt and running. New restorations take place under Don Biagio Peroni (1707- 1794), assistant priest of St. Nicola and chaplain of St. Anthony of Padua, which, given the modest size of the church and its inadequacy in hosting all the faithful, erects, together with his uncle and the pastor D. Filippo Peroni, a second church, which is dedicated to the Addolorata. In his testament of March 4^th, 1756, the sixty-eight Filippo Tabussi, in relation to this church, leaves to his own grandchildren (sons of Domenico Tabussi and Agnese Vannozzi) “a legacy of six festive masses for a chaplaincy” (cleric benefit set up by a faithful with a donation or will, whose revenues are used for worship, often with the obligation to celebrate masses). In the second half of the eighteenth century Friar Giuseppe Taurelli becomes rector, who recalls the eponymous notary of  Monteleone known by acts spread out between 1726 and 1735. The new Church of St. Anthony is founded on a piece of land originally belonging to the convent of Franciscans, who for the first time maintain the prerogative of choosing the chaplain. The order symbol which stands on the façade is a further proof: an oval shield marble, framed by a rope with four nodes containing a cross, under which two crossed arms are carved with open palms, one belonging to St. Francis of Assisi and the other to Christ, and at the bottom the initial "S. F. "indicating Saint Francis. The same marble depiction, although with slight variations, is on the main entrance of St. Francis in Monteleone. The birth of the Franciscan coat of arms dates back to the late fifteenth century on design of St. Bonaventure from Bagnoregio, eminent theologian of the Franciscan order, who lived between 1217/21 and 1274. In a first version, there is not the cross, but only two hands crossed and nailed by a single nail; the version with the cross spreads around the seventeenth and eighteenth century. The essential gabled building is poorly decorated, with plastered walls, a small bell tower and a simple portal with simple stone doorposts and lintel, with a shelf. The interior has a single nave and covered with trusses, while in the back, at a lower level, there is the entrance in a vaulted room, now used as a deposit. The worship room, completely and solidly restored in recent years with the earthquake provisions according to the Law of 19.09.1979, preserves an altarpiece in stucco of the eighteenth century, painted in faux marble and decorated with floral motifs relief. The chief altar has the inscription "ET PETUNT ACCIPIUNT" (they ask and they receive), an expression taken from "Sequeri" (Latin for "It quaeri miraculas"), a popular prayer dedicated to Antonio of Padua, the patron of those who seek lost objects, which traditionally is recited for thirteen consecutive times (hence the nickname "Tredicina di Sant’Antonio").The altar, restored in 1994, is characterized by a canvas of the Madonna with the Child, seated on a throne of clouds and surrounded by angels. She appears to the Holy patron, to whom Jesus gives a lily. In the background some architectures differ in perspective and, at the bottom left, there are three mountains (they probably refers to the client). Next to the altar there are two niches with modern statues of St. Anthony of Padua and the Sacred Heart of Jesus. In the past, the feast of St. Anthony of Padua was celebrated on June 13^th with great solemnity and popular participation. On that occasion, the church floor was covered with red poppies, while a special mutual assistance association, devoted to the Saint, provided to embellish the animals with bows and leaves. The church, surveyed as a building belonging to the Diocese of Spoleto mistakenly under the title of "St. Antonio Abate ", is opened for worship as a subsidiary of the parish of St. Nicola.